منابع مشابه
Hemodynamic effects of red blood cell aggregation.
The influence of red blood cell (RBC) aggregation on blood flow in vivo has been under debate since early 1900's, yet a full understanding has still has not been reached. Enhanced RBC aggregation is well known to increase blood viscosity measured in rotational viscometers. However, it has been demonstrated that RBC aggregation may decrease flow resistance in cylindrical tubes, due to the format...
متن کاملRheology of red blood cell aggregation by computer simulation
The aggregation of red blood cells (RBC) induced by the interactions between RBCs is a dominant factor of the in vitro rheological properties of blood, and existing models of blood do not contain full cellular information. In this work, we introduce a new three-dimensional model that couples Navier–Stokes equations with cell interactions to investigate RBC aggregation and its effect on blood rh...
متن کاملExperimental Pulmonary Embolism Due to Red Cell Aggregation.
The effect of clumping or aggregation of red blood cells on flow has recently become of increasing interest. Unimpeded flow through the capillaries depends to a great extent upon the red cells remaining separate in the plasma. Clumping causes blockage of the blood vessels, the extent of which is governed by the rate of flow and perfusion pressure, and the relative size of the clumps and lumen o...
متن کاملEffects of red blood cell aggregation on myocardial hematocrit gradient using two approaches to increase aggregation.
The normal transmyocardial tissue hematocrit distribution (i.e., subepicardial greater than subendocardial) is known to be affected by red blood cell (RBC) aggregation. Prior studies employing the use of infused large macromolecules to increase erythrocyte aggregation are complicated by both increased plasma viscosity and dilution of plasma. Using a new technique to specifically alter the aggre...
متن کاملInfluence of the red blood cell Ca2+-ion concentration on the erythrocyte aggregation in stasis.
Ca2+ ions were transported into the cell by incubation of the erythrocyte suspension with ionophore A23187, a lipophil electric neutral ion complexing substance. Erythrocyte aggregation could be increased twice, when doubling the intracellular Ca2+-ion concentration. Our measurements lead to the suggestion that an increase of the cytoplasmatic Ca2+ ion changes the physical and/or biochemical pr...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198510000-00311